1. Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan, Department of Cosmetology, Pusan Women’s College, Pusanjin-Gu, Busan, Korea, and Department of Food Science and Nutrition, Research Institute of Ecology for the Elderly, Pusan National University, 30 Jangjeon-dong, Geumjeong-gu, Busan 609-735, Korea