Modeling the Role of G12V and G13V Ras Mutations in the Ras-GAP-Catalyzed Hydrolysis Reaction of Guanosine Triphosphate
Author:
Affiliation:
1. Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow 119991, Russian Federation
2. N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygina 4, Moscow 119334, Russian Federation
Funder
Russian Science Foundation
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi5011333
Reference55 articles.
1. G proteins, effectors and GAPs: structure and mechanism
2. Guanosine triphosphatase stimulation of oncogenic Ras mutants
3. Targeting RAS signalling pathways in cancer therapy
4. The Ras Superfamily of Small GTPases: The Unlocked Secrets
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