Identification of S-(n-Butylcarbamoyl)glutathione, a Reactive Carbamoylating Metabolite of Tolbutamide in the Rat, and Evaluation of Its Inhibitory Effects on Glutathione Reductase in Vitro-Reference-Cited by-同舟云学术

Identification of S-(n-Butylcarbamoyl)glutathione, a Reactive Carbamoylating Metabolite of Tolbutamide in the Rat, and Evaluation of Its Inhibitory Effects on Glutathione Reductase in Vitro

Published:1999-11-10 Issue:12 Volume:12 Page:1138-1143
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Guan Xiangming¹,Davis Margaret R.¹,Tang Cuyue¹,Jochheim Claudia M.¹,Jin Lixia¹,Baillie Thomas A.¹

Affiliation:

1. Pharmaceutical Sciences Department, College of Pharmacy, South Dakota State University, Brookings, South Dakota 57007, Cerep Corporation, 15318 Northeast 95th Street, Redmond, Washington 98052, Department of Drug Metabolism, Merck Research Laboratories, WP75A-303, West Point, Pennsylvania 19486, and Immunex Corporation, 51 University Street, Seattle, Washington 98101

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx990086d

Reference32 articles.

1. Neonatal thrombocytopeniaand congenital malformations associated with administration of tolbutamide to the mother

2. The effect of tolbutamide on rat embryonic development in vitro

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