1. Biomedical Research Institute, Hasselt University, and School of Life Sciences, transnationale Universiteit Limburg, Diepenbeek, Belgium, Department of Mathematics-Physics-Informatics, Theoretical Computer Sciences, Hasselt University, Diepenbeek, Belgium, Faculty of Applied Sciences, Analytical Biotechnology Group, Delft University of Technology, Delft, The Netherlands, and Department of Neurology, University Hospital Maastricht, Maastricht, The Netherlands