An Efficient Synthesis of Pyrrolo[2,3-d]pyrimidines via Inverse Electron Demand Diels−Alder Reactions of 2-Amino-4-cyanopyrroles with 1,3,5-Triazines
Author:
Affiliation:
1. Department of Medicinal Chemistry, Metabasis Therapeutics, Inc., 9390 Towne Centre Drive, Suite 300, San Diego, California 92121 dang@mbasis.com
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo026309d
Reference12 articles.
1. Incorporation of 2′-Deoxysangivamycin in DNA Duplexes: The Conversion of a Pyrrolo[2, 3-d]Pyrimidine Nitrile to a Carboxamide upon Oligonucleotide Deprotection
2. Adenosine Kinase Inhibitors. 1. Synthesis, Enzyme Inhibition, and Antiseizure Activity of 5-Iodotubercidin Analogues
3. Efficient synthesis of purine analogues: an FeCl3–SiO2-promoted cyclization reaction of 4,5-diaminopyrimidines with aldehydes leading to 6,8,9-trisubstituted purines
4. 5-Aminopyrazoles as Dienophiles in the Inverse Electron Demand Diels−Alder Reactions of 2,4,6-Tris(ethoxy- carbonyl)-1,3,5-triazine: Syntheses of Pyrazolopyrimidines
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