An Asymmetric Synthesis of a Chiral Sulfone Acid with Concomitant Hydrolysis and Oxidation to Enable the Preparation of a Glucokinase Activator-Reference-Cited by-同舟云学术

An Asymmetric Synthesis of a Chiral Sulfone Acid with Concomitant Hydrolysis and Oxidation to Enable the Preparation of a Glucokinase Activator

Published:2012-09-06 Issue:9 Volume:16 Page:1538-1543
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

DeBaillie Amy C.¹²,Magnus Nicholas A.¹²,Laurila Michael E.¹²,Wepsiec James P.¹²,Ruble J. Craig¹²,Petkus Jeffrey J.¹²,Vaid Radhe K.¹²,Niemeier Jeffry K.¹²,Mick Joseph F.¹²,Gunter Thomas Z.¹²

Affiliation:

1. Chemical Product Research and Development, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

2. Discovery Chemistry Research and Technologies, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op300139g

Reference16 articles.

1. World Health Organization Diabetes Statistics. http://www.who.int/mediacentre/factsheet/fs312/en/. Accessed January 4, 2012.

2. American Diabetes Organization. http://www.diabetes.org/diabetes-basics/type-2/facts-about-type-2.html. Accessed January 15, 2012.

3. Assessing the potential of glucokinase activators in diabetes therapy

4. Theoretical Study of the Stereoselective Additions of Chiral Alcohols to Ketenes

5. An Alternative Mechanism for the 1,4-Asymmetric Induction in the Stereoselective Addition of (R)-Pantolactone to 2-Phenylpropylketene

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Progress on transition metal catalyzed asymmetric hydroesterification, hydrocarboxylation, and hydroamidation reactions of olefins;Chemical Society Reviews;2022

2. A Practical and Scalable Synthesis of a Glucokinase Activator via Diastereomeric Resolution and Palladium-Catalyzed C–N Coupling Reaction;Organic Process Research & Development;2017-03-06

3. Reaction Workup;Handbook for Chemical Process Research and Development;2016-10-17

4. Base Reagent Selection;Handbook for Chemical Process Research and Development;2016-10-17

5. Development of an Intermittent-Flow Enantioselective Aza-Henry Reaction Using an Arylnitromethane and Homogeneous Brønsted Acid–Base Catalyst with Recycle;Organic Process Research & Development;2016-02-01