Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43-Reference-Cited by-同舟云学术

Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43

Published:2015-06-22 Issue:13 Volume:6 Page:2608-2615
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Mompeán Miguel¹,Hervás Rubén²³,Xu Yunyao⁴,Tran Timothy H.⁵,Guarnaccia Corrado⁶,Buratti Emanuele⁶,Baralle Francisco⁶,Tong Liang⁵,Carrión-Vázquez Mariano²³,McDermott Ann E.⁴,Laurents Douglas V.¹

Affiliation:

1. Instituto de Química Física Rocasolano, CSIC Serrano 119, 28006 Madrid, Spain

2. Instituto Cajal, CSIC Avda, Doctor Arce 37, E-28002 Madrid, Spain

3. Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA-Nanociencia), Crta. de Cantoblanco no. 8, E-28049 Cantoblanco, Madrid, Spain

4. Department of Chemistry, Columbia University, 344 Havemeyer Hall, New York, New York 10027, United States

5. Department of Biological Sciences, Columbia University, New York, New York 10027, United States

6. International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34149 Trieste, Italy

Funder

Consejo Superior de Investigaciones Científicas

European Commission

Ministero della Salute

Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica

Publisher

American Chemical Society (ACS)

Subject

General Materials Science,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.5b00918

Reference47 articles.

1. TDP-43: gumming up neurons through protein–protein and protein–RNA interactions

2. Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

3. TDP-43 is a key player in the clinical features associated with Alzheimer’s disease

4. An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

5. Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection

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