Single Molecule Force Spectroscopy Reveals Distinctions in Key Biophysical Parameters of αβ T-Cell Receptors Compared with Chimeric Antigen Receptors Directed at the Same Ligand-Reference-Cited by-同舟云学术

Single Molecule Force Spectroscopy Reveals Distinctions in Key Biophysical Parameters of αβ T-Cell Receptors Compared with Chimeric Antigen Receptors Directed at the Same Ligand

Published:2021-08-04 Issue:31 Volume:12 Page:7566-7573
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Banik Debasis¹^ORCID,Hamidinia Maryam²³⁴,Brzostek Joanna²³⁴,Wu Ling²³⁴,Stephens Hannah M.¹,MacAry Paul A.²³⁴,Reinherz Ellis L.⁵⁶,Gascoigne Nicholas R. J.²³⁴,Lang Matthew J.¹⁷^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States

2. Translational Immunology Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore

3. Translational Cancer Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore

4. Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore

5. Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, United States

6. Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, United States

7. Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee 37235, United States

Funder

National Medical Research Council

Ministry of Education - Singapore

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

General Materials Science,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.1c02240

Reference44 articles.