Chimeric antigen receptor signaling: Functional consequences and design implications-Reference-Cited by-同舟云学术

Chimeric antigen receptor signaling: Functional consequences and design implications

Published:2020-05-22 Issue:21 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Lindner S. E.¹^ORCID,Johnson S. M.¹,Brown C. E.²^ORCID,Wang L. D.¹³^ORCID

Affiliation:

1. Department of Immuno-Oncology, Beckham Research Institute, City of Hope National Medical Center, Duarte, CA, USA.

2. Department of Hematology and Hematopoietic Cell Transplantation, Beckham Research Institute, City of Hope National Medical Center, Duarte, CA, USA.

3. Department of Pediatrics, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA.

Abstract

CAR signaling may incorporate emergent properties not accurately modeled by TCR signaling frameworks.

Funder

National Cancer Institute

California Institute for Regenerative Medicine

Ben and Catherine Ivy Foundation

Hyundai Hope On Wheels

B+ Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference87 articles.

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4. Expression of chimeric receptor composed of immunoglobulin-derived V resions and T-cell receptor-derived C regions

5. The promise and potential pitfalls of chimeric antigen receptors

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