Synthesis of Multisubstituted 2-Aminopyrroles/pyridines via Chemoselective Michael Addition/Intramolecular Cyclization Reaction
Author:
Affiliation:
1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China
Funder
National Natural Science Foundation of China
Ministry of Science and Technology of the People's Republic of China
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol5018855
Reference40 articles.
1. Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors
2. Synthesis and in vitro antitumoral activity of new hydrazinopyrimidine-5-carbonitrile derivatives
3. Tumor-Targeting with Novel Non-Benzoyl 6-Substituted Straight Chain Pyrrolo[2,3-d]pyrimidine Antifolates via Cellular Uptake by Folate Receptor α and Inhibition of de Novo Purine Nucleotide Biosynthesis
4. Evaluation of the anti-inflammatory activity of some pyrrolo[2,3-d]pyrimidine derivatives
5. Synthesis of 5,7-disubstituted-4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amines as microtubule inhibitors
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