The Unexpected and Exceptionally Facile Chemical Modification of the Phenolic Hydroxyl Group of Tyrosine by Polyhalogenated Quinones under Physiological Conditions

Author:

Qu Na1,Li Feng1,Shao Bo1,Shao Jie1,Zhai Guijin23,Wang Fuyi2,Zhu Ben-Zhan1

Affiliation:

1. State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Centre for Eco-environmental Sciences and University of the Chinese Academy of Sciences, the Chinese Academy of Sciences, 18 Shuangqin Road, Haidian District, Beijing 100085, P. R. China

2. Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China

3. Tianjin Research Centre of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, P. R. China

Funder

National Institute of Environmental Health Sciences

National Center for Research Resources

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

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