Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation-Reference-Cited by-同舟云学术

Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation

Published:2016-11-28 Issue:12 Volume:29 Page:2136-2144
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Dekker Stefan J.¹,Zhang Yongjie¹,Vos J. Chris¹,Vermeulen Nico P. E.¹,Commandeur Jan N. M.¹

Affiliation:

1. Division of Molecular Toxicology, Amsterdam Institute for Molecules Medicine and Systems (AIMMS), Vrije Universiteit, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands

Funder

European Commission

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.6b00250

Reference54 articles.

1. Nevirapine

2. Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection

3. Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy

4. Evidence of an Immune-Mediated Mechanism for an Idiosyncratic Nevirapine-Induced Reaction in the Female Brown Norway Rat

5. Demonstration of the Metabolic Pathway Responsible for Nevirapine-Induced Skin Rash

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