Quantitative Evaluation of Reactivity and Toxicity of Acyl Glucuronides by [35S]Cysteine Trapping
Author:
Affiliation:
1. Central Research Laboratories, Kissei Pharmaceutical Co., Ltd., 4365-1, Hotaka-Kashiwabara, Azumino, Nagano 399-8304, Japan
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00111
Reference43 articles.
1. Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic Drugs
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3. Genotoxicity of Acyl Glucuronide Metabolites Formed from Clofibric Acid and Gemfibrozil: A Novel Role for Phase-II-Mediated Bioactivation in the Hepatocarcinogenicity of the Parent Aglycones?
4. Acyl glucuronide reactivity in perspective: biological consequences
5. Acyl Glucuronides: Biological Activity, Chemical Reactivity, and Chemical Synthesis
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