Impact of E-Cigarette Liquid Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, the Primary Nicotine-Metabolizing Enzyme-Reference-Cited by-同舟云学术

Impact of E-Cigarette Liquid Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, the Primary Nicotine-Metabolizing Enzyme

Published:2020-06-04 Issue:7 Volume:33 Page:1689-1697
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Winters Brett R.¹²,Kochar Tavleen K.³,Clapp Phillip W.⁴,Jaspers Ilona¹⁴^ORCID,Madden Michael C.⁵^ORCID

Affiliation:

1. Curriculum in Toxicology and Environmental Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, United States

2. GSI Environmental Inc., Oakland, California 94612, United States

3. Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, United States

4. Center for Environmental Medicine, Asthma, and Lung Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, United States

5. Public Health and Integrative Toxicology Division, Office of Research and Development, United States Environmental Protection Agency, Chapel Hill, North Carolina 27514, United States

Funder

National Heart, Lung, and Blood Institute

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00514

Reference37 articles.

1. CYP2A6: genetics, structure, regulation, and function

2. Padmanabhan, S. (2014) Handbook of Pharmacogenomics and Stratified Medicine, p 1093, Elsevier, Amsterdam.

3. Human Extrahepatic Cytochromes P450: Function in Xenobiotic Metabolism and Tissue-Selective Chemical Toxicity in the Respiratory and Gastrointestinal Tracts

4. Differential Distribution of CYP2A6 and CYP2A13 in the Human Respiratory Tract

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