Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes

Author:

Kovarik Zrinka1,Maček Hrvat Nikolina1,Katalinić Maja1,Sit Rakesh K.2,Paradyse Alexander3,Žunec Suzana1,Musilek Kamil4,Fokin Valery V.2,Taylor Palmer3,Radić Zoran3

Affiliation:

1. Institute for Medical Research and Occupational Health, Ksaverska cesta 2, HR-10000 Zagreb, Croatia

2. Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States,

3. Department of Pharmacology, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California at San Diego, La Jolla, California 92093-0650, United States

4. Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic

Funder

National Institute of Neurological Disorders and Stroke

Ministarstvo Obrazovanja, Znanosti i Sporta

Hrvatska Zaklada za Znanost

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

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