Toxicity Originating from Thiophene Containing Drugs: Exploring the Mechanism using Quantum Chemical Methods
Author:
Affiliation:
1. Department of Medicinal Chemistry and ‡Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, S. A. S. Nagar (Mohali), 160 062 Punjab, India
Funder
Department of Biotechnology , Ministry of Science and Technology
Department of Science and Technology, Ministry of Science and Technology
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.5b00364
Reference117 articles.
1. Predicting Toxicities of Reactive Metabolite–Positive Drug Candidates
2. Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks
3. The Generation, Detection, and Effects of Reactive Drug Metabolites
4. Applying Mechanisms of Chemical Toxicity to Predict Drug Safety
5. Bioactivation of Drugs: Risk and Drug Design
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