Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis
Author:
Affiliation:
1. Vilnius University Institute of Biochemistry, Mokslininku st. 12, LT-08662 Vilnius, Lithuania
Funder
Lietuvos Mokslo Taryba
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.5b00336
Reference101 articles.
1. RH1 Induces Cellular Damage in an NAD(P)H:Quinone Oxidoreductase 1-Dependent Manner: Relationship between DNA Cross-linking, Cell Cycle Perturbations, and Apoptosis
2. Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity
3. Diaziridinylbenzoquinones
4. Preclinical efficacy of the bioreductive alkylating agent RH1 against paediatric tumours
5. DT-diaphorase: a target for new anticancer drugs
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