Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements-Reference-Cited by-同舟云学术

Formation of DHP-DNA Adducts from Rat Liver Microsomal Metabolism of 1,2-Unsaturated Pyrrolizidine Alkaloid-Containing Plant Extracts and Dietary Supplements

Published:2023-01-27 Issue:2 Volume:36 Page:243-250
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

He Xiaobo¹^ORCID,Xia Qingsu¹,Zhu Lin²,He Yisheng²^ORCID,Bryant Matthew S.¹,Lin Ge²^ORCID,Fu Peter P.¹^ORCID

Affiliation:

1. National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas 72079, United States

2. School of Biomedical Science, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, The People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.2c00321

Reference40 articles.

1. Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms

2. Pyrrolizidine alkaloids - Tumorigenic components in Chinese herbal medicines and dietary supplements

3. Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China

4. Identification of five hepatotoxic pyrrolizidine alkaloids in a commonly used traditional Chinese medicinal herb, Herba Senecionis scandentis (Qianliguang)

5. Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease

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1. A computational study of the structures and base-pairing properties of pyrrolizidine alkaloid-derived DNA adducts;Canadian Journal of Chemistry;2023-12-21

2. Pyrrolizidine Alkaloids—Pros and Cons for Pharmaceutical and Medical Applications;International Journal of Molecular Sciences;2023-11-30