Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation-Reference-Cited by-同舟云学术

Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation

Published:2018-06-01 Issue:7 Volume:31 Page:619-628
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Xia Qingsu¹,He Xiaobo¹,Ma Liang¹,Chen Shoujun¹,Fu Peter P.¹^ORCID

Affiliation:

1. National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079, United States

Funder

Oak Ridge Institute for Science and Education

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00096

Reference42 articles.

1. Primary Liver Tumours in Rats following Feeding with Alkaloids of Senecio jacobaea

2. Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease

3. Pyrrolizidine Alkaloids: Metabolic Activation Pathways Leading to Liver Tumor Initiation

4. High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Pyrrolizidine Alkaloid-Derived DNA Adducts in Vitro and in Vivo

5. GENOTOXIC PYRROLIZIDINE ALKALOIDS AND PYRROLIZIDINE ALKALOIDN-OXIDES—MECHANISMS LEADING TO DNA ADDUCT FORMATION AND TUMORIGENICITY

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