Synthesis of Pyridopyrimidines by Palladium-Catalyzed Isocyanide Insertion

Author:

Estévez Verónica1,Van Baelen Gitte1,Lentferink Babette H.1,Vlaar Tjøstil1,Janssen Elwin1,Maes Bert U. W.2,Orru Romano V. A.1,Ruijter Eelco1

Affiliation:

1. Department of Chemistry & Pharmaceutical Sciences and Amsterdam Institute for Molecules, Medicines & Systems, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands

2. Organic Synthesis, Department of Chemistry, University of Antwerp, Groenenborgerlaan 171, B-2020, Antwerp, Belgium

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Reference24 articles.

1. Comprehensive analysis of kinase inhibitor selectivity

2. aBakthavatchalam, R.; Blum, C. A.; Chenard, B. L.Neurogen Corp.; WO Patent WO2005/23807 A2; 2005.

3. bPomel, V.; Gaillard, P.; Desforges, G.; Quattropani, A.; Montagne, C.Merck Serono; WO Patent WO2010/37765 A2; 2010.

4. cDugar, S.; Chakravarty, S.; Murphy, A.; McEnroe, G.; Conte, A.; Perumattam, J. J.Scios Inc.; WO Patent WO2005/32481 A2; 2005.

5. Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

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