1. Research Center for Ethnomedicines, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan, Medical College, Three Gorges University, Yichang, Hubei 443003, People's Republic of China, and School of Pharmaceutical Sciences, Peking University, 38 Xue-yuan Road, Haidian District, Beijing 100083, People's Republic of China