Strong Feedback Inhibition of Key Enzymes in the Morphine Biosynthetic Pathway from Opium Poppy Detectable in Engineered Yeast
Author:
Affiliation:
1. Department of Biological Sciences, University of Calgary, Calgary, Alberta T2N 1N4, Canada
Funder
Genome Alberta
Alberta Innovates
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00873
Reference77 articles.
1. Back to the plant: overcoming roadblocks to the microbial production of pharmaceutically important plant natural products
2. Engineering Plant Secondary Metabolism in Microbial Systems
3. Complete biosynthesis of opioids in yeast
4. De novo production of the key branch point benzylisoquinoline alkaloid reticuline in yeast
5. Complete biosynthesis of noscapine and halogenated alkaloids in yeast
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