Mitochondrial Targeting of Doxorubicin Eliminates Nuclear Effects Associated with Cardiotoxicity
Author:
Affiliation:
1. Department of Oncology, University of Torino, via Santena 5/bis, 10126 Torino, Italy
2. Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada
Funder
Canadian Institutes of Health Research
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acschembio.5b00268
Reference41 articles.
1. Targeting DNA topoisomerase II in cancer chemotherapy
2. Drugging Topoisomerases: Lessons and Challenges
3. Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity
4. Doxorubicin-Induced Cardiomyopathy
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