Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons-Reference-Cited by-同舟云学术

Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons

Published:2020-11-18 Issue:12 Volume:15 Page:3149-3158
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Matyskiela Mary E¹,Zhu Jinyi¹,Baughman Joshua M¹,Clayton Thomas¹,Slade Michelle¹,Wong Hon Kit²,Danga Kristina¹,Zheng Xinde¹,Labow Mark²,LeBrun Laurie¹,Lu Gang¹,Chamberlain Philip P¹,Thompson Joel W¹^ORCID

Affiliation:

1. Bristol Myers Squibb Company, San Diego, California 92121, United States

2. Bristol Myers Squibb CompanyCambridgeMassachusetts02140United States

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.0c00674

Reference40 articles.

1. Drugging the undruggables: exploring the ubiquitin system for drug development

2. Development of targeted protein degradation therapeutics

3. Multispecific drugs herald a new era of biopharmaceutical innovation

4. Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality

5. PROTACs: great opportunities for academia and industry

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