Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality-Reference-Cited by-同舟云学术

Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality

Published:2019-11-12 Issue:12 Volume:10 Page:1592-1602
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Chamberlain Philip P.¹^ORCID,D’Agostino Laura A.¹,Ellis J. Michael¹,Hansen Joshua D.¹^ORCID,Matyskiela Mary E.¹,McDonald Joseph J.¹,Riggs Jennifer R.¹^ORCID,Hamann Lawrence G.¹^ORCID

Affiliation:

1. Celgene Corporation, 200 Cambridge Park Drive, Suite 3000, Cambridge, Massachusetts 02140, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00425

Reference86 articles.

1. Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery?

2. Brefeldin A

3. Crystal Structure of ARF1•Sec7 Complexed with Brefeldin A and Its Implications for the Guanine Nucleotide Exchange Mechanism

4. Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor

5. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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