Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor-Reference-Cited by-同舟云学术

Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor

Published:2021-05-13 Issue:6 Volume:16 Page:1030-1039
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Ragunathan Priya¹,Cole Malcolm²,Latka Chitra¹,Aragaw Wassihun Wedajo³,Hegde Pooja²,Shin Joon¹,Subramanian Manimekalai Malathy Sony¹,Rishikesan Sankaranarayanan¹,Aldrich Courtney C.²^ORCID,Dick Thomas³⁴⁵,Grüber Gerhard¹^ORCID

Affiliation:

1. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Republic of Singapore

2. University of Minnesota, College of Pharmacy, Department of Medicinal Chemistry 8-101 Weaver-Densford Hall 308 Harvard St. SE, Minneapolis, Minnesota 55455, United States

3. Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, New Jersey 07110, United States

4. Department of Medical Sciences, Hackensack Meridian School of Medicine, 123 Metro Boulevard, Nutley, New Jersey 07110, United States

5. Department of Microbiology and Immunology, Georgetown University, 3900 Reservoir Road NW Medical-Dental Building, Washington, District of Columbia 20007, United States

Funder

National Institute of Allergy and Infectious Diseases

National Research Foundation Singapore

Singapore Ministry of Education Academic Research Fund Tier 1

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00131

Reference28 articles.

1. Expression of the Corynebacterium glutamicum panD Gene Encoding l -Aspartate-α-Decarboxylase Leads to Pantothenate Overproduction in Escherichia coli