The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity-Reference-Cited by-同舟云学术

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

Published:2021-09-28 Issue:11 Volume:16 Page:2401-2414
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Mostert Konrad J.¹,Sharma Nandini²,van der Zwaag Marianne³,Staats Roxine¹,Koekemoer Lizbé¹,Anand Ruchi²^ORCID,Sibon Ody C. M.³,Strauss Erick¹^ORCID

Affiliation:

1. Department of Biochemistry, Stellenbosch University, Stellenbosch, 7600, South Africa

2. Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India

3. Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, 9713 AV, The Netherlands

Funder

National Institute of Allergy and Infectious Diseases

Department of Science and Technology, Ministry of Science and Technology, India

National Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.1c00535

Reference49 articles.

1. Acetyl Coenzyme A: A Central Metabolite and Second Messenger

2. Defective pantothenate metabolism and neurodegeneration

3. Deregulated coenzyme A, loss of metabolic flexibility and diabetes

4. Coenzyme A, more than ‘just’ a metabolic cofactor

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