GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs-Reference-Cited by-同舟云学术

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GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs

Published:2019-02-14 Issue:3 Volume:14 Page:348-355
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Zahreddine Hiba Ahmad¹,Culjkovic-Kraljacic Biljana¹,Gasiorek Jadwiga¹,Duchaine Jean¹,Borden Katherine L. B.¹^ORCID

Affiliation:

1. Institute for Research in Immunology and Cancer and Department of Pathology and Cell Biology, Université de Montréal, Montréal, Quebec, Canada

Funder

Leukemia and Lymphoma Society of Canada

Canadian Institutes of Health Research

National Institutes of Health

Canada Research Chairs

Leukemia and Lymphoma Society

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.8b01118

Reference30 articles.

1. Mechanisms and insights into drug resistance in cancer

2. A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

3. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

4. The UGT2B28 Sex-steroid Inactivation Pathway Is a Regulator of Steroidogenesis and Modifies the Risk of Prostate Cancer Progression

5. Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells

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1. GLI1 polymorphisms influence remission rate and prognosis of young de novo acute myeloid leukemia patients treated with cytarabine-based chemotherapy;Annals of Hematology;2024-04-27

2. Medicinal Chemistry and NMR Driven Discovery of Novel UDP-glucuronosyltransferase 1A Inhibitors That Overcome Therapeutic Resistance in Cells;Journal of Molecular Biology;2024-01

3. A novel approach to overcome drug resistance in acute myeloid leukemia;Haematologica;2023-05-11

4. 1,3,8-Triazaspiro[4.5]decane Derivatives Inhibit Permeability Transition Pores through a FO-ATP Synthase c Subunit Glu119-Independent Mechanism That Prevents Oligomycin A-Related Side Effects;International Journal of Molecular Sciences;2023-03-24

5. Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine;Haematologica;2023-03-23

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