A novel approach to overcome drug resistance in acute myeloid leukemia
Author:
Publisher
Ferrata Storti Foundation (Haematologica)
Subject
Hematology
Reference13 articles.
1. Assouline S, Gasiorek J, Bergeron J. Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine. Haematologica. 2023; 108(11):2946-2958.
2. Zhang J, Gu Y, Chen B. Mechanisms of drug resistance in acute myeloid leukemia. Onco Targets Ther. 2019; 12:1937-1945.
3. Assouline S, Culjkovic B, Cocolakis E. Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin. Blood. 2009; 114(2):257-260.
4. Zahreddine HA, Culjkovic-Kraljacic B, Assouline S. The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation. Nature. 2014; 511(7507):90-93.
5. Allain EP, Rouleau M, Levesque E, Guillemette C. Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression. Br J Cancer. 2020; 122(9):1277-1287.
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