X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors-Reference-Cited by-同舟云学术

X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors

Published:2019-11-12 Issue:12 Volume:14 Page:2810-2821
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Arnst Kinsie E.¹,Banerjee Souvik¹,Wang Yuxi²,Chen Hao¹,Li Yong³,Yang Lei³,Li Weimin²,Miller Duane D.¹^ORCID,Li Wei¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

3. Analytical Technologies Center, Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

Funder

U.S. Department of Health and Human Services

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00696

Reference29 articles.

1. Microtubules

2. Microtubules and resistance to tubulin-binding agents

3. Microtubule destabilising agents: far more than just antimitotic anticancer drugs

4. Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site

5. The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of novel thiophene[3,2-d]pyrimidine-based tubulin inhibitors with enhanced antitumor efficacy for combined use with anti-pd-l1 immunotherapy in melanoma;European Journal of Medicinal Chemistry;2024-11

2. Podophyllotoxin derivatives-tubulin complex reveals a potential binding site of tubulin polymerization inhibitors in α-tubulin adjacent to colchicine site;International Journal of Biological Macromolecules;2024-09

3. Quinoxaline derivatives: Recent discoveries and development strategies towards anticancer agents;European Journal of Medicinal Chemistry;2024-05

4. Verubulin (Azixa) Analogues with Increased Saturation: Synthesis, SAR and Encapsulation in Biocompatible Nanocontainers Based on Ca2+ or Mg2+ Cross-Linked Alginate;Pharmaceuticals;2023-10-21

5. Fused Imidazopyrazine-Based Tubulin Polymerization Inhibitors Inhibit Neuroblastoma Cell Function;ACS Medicinal Chemistry Letters;2023-08-25