Fused Imidazopyrazine-Based Tubulin Polymerization Inhibitors Inhibit Neuroblastoma Cell Function
Author:
Affiliation:
1. Department of Chemistry, Middle Tennessee State University, Murfreesboro, Tennessee 37132, United States
2. Department of Biology, Middle Tennessee State University, Murfreesboro, Tennessee 37132, United States
Funder
National Cancer Institute
Middle Tennessee State University
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00298
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1. Understanding microtubule dynamics for improved cancer therapy
2. Structural Basis of cis- and trans-Combretastatin Binding to Tubulin
3. Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy
4. X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors
5. In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents
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