Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase-Reference-Cited by-同舟云学术

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase

Published:2017-08-29 Issue:9 Volume:12 Page:2448-2456
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Santa Maria John P.¹^ORCID,Park Yumi²,Yang Lihu³,Murgolo Nicholas⁴,Altman Michael D.¹,Zuck Paul⁵,Adam Greg⁶,Chamberlin Chad⁷,Saradjian Peter⁷,Dandliker Peter⁷,Boshoff Helena I. M.²,Barry Clifton E.²,Garlisi Charles⁸,Olsen David B.⁹,Young Katherine⁹,Glick Meir¹,Nickbarg Elliott⁷,Kutchukian Peter S.¹^ORCID

Affiliation:

1. Modeling & Informatics, Merck Research Laboratories, Boston, Massachusetts, United States

2. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States

3. Department of Chemistry, Merck Sharp & Dohme Corp., Kenilworth, New Jersey, United States

4. Department of Information & Analytics, Merck Sharp & Dohme Corp., Kenilworth, New Jersey, United States

5. Research Science, Merck Sharp & Dohme Corp., North Wales, Pennsylvania, United States

6. Department of Pharmacology, Merck Sharp & Dohme Corp., North Wales, Pennsylvania, United States

7. Department of Pharmacology, Merck Sharp & Dohme Corp., Boston, Massachusetts, United States

8. Department of Pharmacology, Merck Sharp & Dohme Corp., Kenilworth, New Jersey, United States

9. Neglected Tropical Disease Discovery, Merck Sharp & Dohme Corp., West Point, Pennsylvania, United States

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00468

Reference35 articles.

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