Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity-Reference-Cited by-同舟云学术

Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity

Published:2023-02-16 Issue:3 Volume:18 Page:583-594
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Quek Rui Tong¹²^ORCID,Hardy Kierra S.¹²,Walker Stephen G.³,Nguyen Dan T.¹²^ORCID,de Almeida Magalhães Taciani⁴,Salic Adrian⁴,Gopalakrishnan Sujatha M.³,Silver Pamela A.¹²^ORCID,Mitchison Timothy J.¹

Affiliation:

1. Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States

2. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts 02115, United States

3. Drug Discovery Science and Technology, AbbVie Inc., North Chicago, Illinois 60064, United States

4. Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.2c00908

Reference55 articles.

1. Protein Phase Separation: A New Phase in Cell Biology

2. Biomolecular condensates: organizers of cellular biochemistry

3. Liquid phase condensation in cell physiology and disease

4. Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates

5. Negri bodies are viral factories with properties of liquid organelles

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