A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells-Reference-Cited by-同舟云学术

A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells

Published:2016-01-08 Issue:4 Volume:11 Page:921-930
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Matheson Christopher J.¹,Venkataraman Sujatha²,Amani Vladimir²,Harris Peter S.²,Backos Donald S.¹,Donson Andrew M.²,Wempe Michael F.¹,Foreman Nicholas K.²,Vibhakar Rajeev²,Reigan Philip¹

Affiliation:

1. Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, V20-2102, Aurora, Colorado 80045, United States

2. Department of Pediatrics and Section of Pediatric Hematology/Oncology/BMT, University of Colorado Anschutz Medical Campus, 12800 E 19th Ave, Mail Stop 8302, Aurora, Colorado 80045, United States

Funder

National Center for Advancing Translational Sciences

National Institute of Neurological Disorders and Stroke

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.5b00725

Reference48 articles.

1. The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials

2. Progress and Challenges in Childhood Brain Tumors