Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway-Reference-Cited by-同舟云学术

Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway

Published:2019-10-08 Issue: Volume: Page:
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Ottis Philipp,Palladino Chiara,Thienger Phillip,Britschgi Adrian,Heichinger Christian,Berrera Marco,Julien-Laferriere Alice,Roudnicky Filip,Kam-Thong Tony,Bischoff James R.,Martoglio Bruno,Pettazzoni Piergiorgio^ORCID

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00525

Reference39 articles.

1. Small-Molecule Modulation of Protein Homeostasis

2. Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones?

3. The PROTAC technology in drug development

4. Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy

5. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

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