Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC)

Author:

Zhang Jianchao1ORCID,Chen Xiao1,Chen Congli2,Li Fengming3,Song Xiaoxiao1,Liu Chaowei1,Liao Kefan1,Su Ming-Yuan145,Tan Chris Soon Heng3ORCID,Fang Lijing2ORCID,Rao Hai14

Affiliation:

1. Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Shenzhen 518055, China

2. Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key Laboratory of Biomedical Imaging Science and System, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen 518055, China

3. Department of Chemistry, Southern University of Science and Technology, Shenzhen 518055, China

4. Key University Laboratory of Metabolism and Health of Guangdong, Southern University of Science and Technology, Shenzhen 518055, China

5. Institute for Biological Electron Microscopy, Southern University of Science and Technology, Shenzhen 518055, China

Funder

National Key Research and Development Program of China

Shenzhen Fundamental Research Program

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Key Talent Program of Guangdong

High level of special funds

Medical Research Innovation Project

Publisher

American Chemical Society (ACS)

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