Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect-Reference-Cited by-同舟云学术

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect

Published:2021-01-13 Issue:2 Volume:16 Page:334-343
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Warminski Marcin¹^ORCID,Kowalska Joanna¹^ORCID,Nowak Elzbieta²,Kubacka Dorota¹,Tibble Ryan³,Kasprzyk Renata⁴,Sikorski Pawel J.⁴,Gross John D.³,Nowotny Marcin²^ORCID,Jemielity Jacek⁴^ORCID

Affiliation:

1. Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland

2. Laboratory of Protein Structure, International Institute of Molecular and Cell Biology, Ksiecia Trojdena 4, 02-109 Warsaw, Poland

3. Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California 94158, United States

4. Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland

Funder

Ministerstwo Nauki i Szkolnictwa Wyzszego

Narodowe Centrum Nauki

Fundacja na rzecz Nauki Polskiej

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acschembio.0c00864

Reference59 articles.

1. Phosphorothioate Analogues of Nucleotides?Tools for the Investigation of Biochemical Processes

2. Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

3. Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis

4. Phosphorothioate modified oligonucleotide–protein interactions

5. In vivo mRNA imaging based on tripartite DNA probe mediated catalyzed hairpin assembly

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Trinucleotide cap analogs with triphosphate chain modifications: synthesis, properties, and evaluation as mRNA capping reagents;Nucleic Acids Research;2024-09-09

2. mRNA vaccine development and applications: A special focus on tumors (Review);International Journal of Oncology;2024-07-09

3. Messenger RNA Therapy for Female Reproductive Health;Molecular Pharmaceutics;2024-01-08

4. An engineered T7 RNA polymerase for efficient co-transcriptional capping with reduced dsRNA byproducts in mRNA synthesis;Faraday Discussions;2024

5. Chemical Modifications of mRNA Ends for Therapeutic Applications;Accounts of Chemical Research;2023-10-02