The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes-Reference-Cited by-同舟云学术

The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes

Published:2020-01-07 Issue:2 Volume:15 Page:437-445
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Lange Joshua¹,Anderson Regan J.²^ORCID,Marshall Andrew J.²,Chan Susanna T. S.²,Bilbrough Timothy S.²,Gasser Olivier¹,Gonzalez-Lopez Claudia³,Salio Mariolina³,Cerundolo Vincenzo³,Hermans Ian F.¹⁴,Painter Gavin F.²⁴^ORCID

Affiliation:

1. Malaghan Institute of Medical Research, Wellington, New Zealand

2. The Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand

3. Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

4. Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand

Funder

Ministry of Business, Innovation and Employment

Health Research Council of New Zealand

Cancer Research UK

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acschembio.9b00902

Reference28 articles.

1. MR1 presents microbial vitamin B metabolites to MAIT cells

2. Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire

3. MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection

4. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

5. Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

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2. Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis;Angewandte Chemie International Edition;2024-06-26

3. Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis;Angewandte Chemie;2024-06-26

4. Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation;Communications Biology;2024-02-24

5. MR1 antigen presentation to MAIT cells and other MR1-restricted T cells;Nature Reviews Immunology;2023-09-29