Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties-Reference-Cited by-同舟云学术

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

Published:2011-08-05 Issue:17 Volume:54 Page:6014-6027
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Flynn Bernard L.¹,Gill Gurmit S.¹,Grobelny Damian W.¹,Chaplin Jason H.¹,Paul Dharam¹,Leske Annabell F.¹,Lavranos Tina C.¹,Chalmers David K.,Charman Susan A.,Kostewicz Edmund,Shackleford David M.,Morizzi Julia,Hamel Ernest²,Jung M. Katherine³,Kremmidiotis Gabriel¹

Affiliation:

1. Bionomics Ltd., 31 Dalgleish Street, Thebarton, South Australia, 5031, Australia

2. Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, United States

3. Division of Metabolism and Health Effects, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200454y

Reference85 articles.

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4. Anticancer therapy with novel tubulin-interacting drugs

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