Triplex Formation by Oligonucleotides Containing 5-(1-Propynyl)-2‘-deoxyuridine:  Decreased Magnesium Dependence and Improved Intracellular Gene Targeting

Author:

Lacroix Laurent1,Lacoste Jérôme1,Reddoch James F.1,Mergny Jean-Louis1,Levy Dan D.1,Seidman Michael M.1,Matteucci Mark D.1,Glazer Peter M.1

Affiliation:

1. Departments of Therapeutic Radiology and Genetics, Yale University, Boyer Center 354, 295 Congress Avenue, New Haven, Connecticut 06536, Laboratoire de Biophysique, Muséum National d'Histoire Naturelle, INSERM U201, CNRS UA481, 43, rue Cuvier, 75005 Paris, France, Food and Drug Administration, 200 C Street, SW, Washington, DC, 20204, National Institute on Aging, NIH, 5600 Nathan Shock Drive, Baltimore, Maryland 21224-6825, and Gilead Sciences, 353 Lakeside Drive, Foster City, California 94404

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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