Exploring Reactive Conformations of Coenzyme A during Binding and Unbinding to Pyruvate Formate

Exploring Reactive Conformations of Coenzyme A during Binding and Unbinding to Pyruvate Formate–Lyase

Published:2019-10-03 Issue:43 Volume:123 Page:9345-9356
ISSN:1089-5639
Container-title:The Journal of Physical Chemistry A
language:en
Short-container-title:J. Phys. Chem. A

Author:

Hanževački Marko¹²,Banhatti Radha Dilip¹,Čondić-Jurkić Karmen¹³,Smith Ana-Sunčana¹²,Smith David M.¹^ORCID

Affiliation:

1. Group for Computational Life Sciences, Division for Physical Chemistry, Ruđer Bošković Institute, Bijenička cesta 54, 10000 Zagreb, Croatia

2. PULS Group, Department of Physics, Interdisciplinary Center for Nanostructured Films, Friedrich-Alexander-Universität Erlangen-Nürnberg, Cauerstraße 3, 91058 Erlangen, Germany

3. Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States

Funder

Hrvatska Zaklada za Znanost

FP7 Ideas: European Research Council

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpca.9b06913

Reference60 articles.

1. Enzyme catalysis: not different, just better

2. Introduction: Principles of Enzymatic Catalysis

3. The Classification and Evolution of Enzyme Function

4. Structural basis for ligand binding to an enzyme by a conformational selection pathway

5. Multiple Conformational Changes in Enzyme Catalysis

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