5-Amino-2-aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors. Part 2. The Impact of Bridging Groups at Position C-2-Reference-Cited by-同舟云学术

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5-Amino-2-aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors. Part 2. The Impact of Bridging Groups at Position C-2

Published:2011-11-23 Issue:24 Volume:54 Page:8517-8525
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lee Hsueh-Yun¹,Chang Jang-Yang²,Nien Chih-Ying¹,Kuo Ching-Chuan²,Shih Kuang-Hsing³,Wu Chun-Hsein⁴,Chang Chi-Yen²,Lai Wen-Yang²,Liou Jing-Ping¹

Affiliation:

1. School of Pharmacy, College of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan, Republic of China

2. National Institute of Cancer Research, National Health Research Institutes, Tainan 704, Taiwan, Republic of China

3. Department of Obstetrics and Gynecology, Cheng Hsin General Hospital, Taipei 11212, Taiwan, Republic of China

4. WU CHUN-HSEIN OB/GYN Clinic, Tainan 70157, Taiwan, Republic of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201031f

Reference49 articles.

1. Discovery and development of antimitotic agents that inhibit tubulin polymerisation for the treatment of cancer

2. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle

3. Medicinal Chemistry of Combretastatin A4: Present and Future Directions

4. Pharmaceutical Design of Antimitotic Agents Based on Combretastatins

5. Antimitotic natural products and their interactions with tubulin

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