Toward Proteome-Scale Identification and Quantification of Isoaspartyl Residues in Biological Samples
Author:
Affiliation:
1. Division of Molecular Biometry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17 177 Stockholm, Sweden
Publisher
American Chemical Society (ACS)
Subject
General Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/pr900428m
Reference36 articles.
1. Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.
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3. Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.
4. Biological Significance of Isoaspartate and Its Repair System
5. Deamidation destabilizes and triggers aggregation of a lens protein, βA3-crystallin
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