Synthesis and Evaluation of cis-1-[4-(Hydroxymethyl)-2-cyclopenten-1-yl]-5-[124I]iodouracil:  A New Potential PET Imaging Agent for HSV1-tk Expression

Author:

Ahn Hyunseok1,Choi Tae Hyun1,De Castro Kathlia1,Lee Kyo Chul1,Kim Byoungsoo1,Moon Byung Seok1,Hong Su Hee1,Lee Jong Chan1,Chun Kwon Soo1,Cheon Gi Jeong1,Lim Sang Moo1,An Gwang Il1,Rhee Hakjune1

Affiliation:

1. Hanyang University, Department of Chemistry and Applied Chemistry, Ansan, Sangrok-Gu, Sa-3-Dong 1271, Kyunggi-Do 426-791, Korea, Laboratory of Radiopharmaceuticals and Laboratory of Nuclear Medicine, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneungdong, Nowongu, Seoul 139-706, Korea, and DMPK Team, Drug Discovery Laboratory, Central Research Institute, Choongwae Pharma Corporation, 146-141 Annyung-Dong, Hwasung-City, Kyunggi-Do, 445-976, Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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