Synthesis of functionalized cyclopentenes through allenic ketone-based multicomponent reactions

Author:

Wang Qiang12345ORCID,Zhang Tao12345,Fan Yunchang12345,Fan Xuesen678910ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Henan Key Laboratory of Coal Green Conversion

3. Henan Polytechnic University

4. Jiaozuo

5. P. R. China

6. Henan Key Laboratory of Organic Functional Molecule and Drug Innovation

7. Collaborative Innovation Centre of Henan Province for Green Manufacturing of Fine Chemicals

8. Key Laboratory of Green Chemical Media and Reactions

9. Ministry of Education

10. School of Chemistry and Chemical Engineering

Abstract

A novel synthesis of cyclopentene and methylenecyclopentane derivatives through the cascade reactions of 4-chloroacetoacetate with malononitrile/cyanoacetate and allenic ketones is presented.

Funder

Education Department of Henan Province

Henan Polytechnic University

Natural Science Foundation of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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