Structure−Activity Relationships of 1,2,4-Benzotriazine 1,4-Dioxides as Hypoxia-Selective Analogues of Tirapazamine-Reference-Cited by-同舟云学术

Structure−Activity Relationships of 1,2,4-Benzotriazine 1,4-Dioxides as Hypoxia-Selective Analogues of Tirapazamine

Published:2002-12-02 Issue:1 Volume:46 Page:169-182
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hay Michael P.¹,Gamage Swarna A.¹,Kovacs Mary S.¹,Pruijn Frederik B.¹,Anderson Robert F.¹,Patterson Adam V.¹,Wilson William R.¹,Brown J. Martin¹,Denny William A.¹

Affiliation:

1. Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand, and Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020367%2B

Reference46 articles.

1. Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays

2. Hypoxic regions exist in human prostate carcinoma

3. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

4. Hypoxia-specific cytotoxins in cancer therapy

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