Antitrypanosomal Activity of 5‘-Deoxy-5‘-(iodomethylene)adenosine and Related 6-N-Cyclopropyladenosine Analogues-Reference-Cited by-同舟云学术

Antitrypanosomal Activity of 5‘-Deoxy-5‘-(iodomethylene)adenosine and Related 6-N-Cyclopropyladenosine Analogues

Published:2006-02-22 Issue:6 Volume:49 Page:2096-2102
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rapp Magdalena¹,Haubrich Trisha A.¹,Perrault Jacques¹,Mackey Zachary B.¹,McKerrow James H.¹,Chiang Peter K.¹,Wnuk Stanislaw F.¹

Affiliation:

1. Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, Department of Biology, San Diego State University, San Diego, California 92182, Department of Pathology and Sandler Center, QB3, University of California, San Francisco, California 94143, and Pharmadyn Inc., Sunnyvale, California 94085

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0511379

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1. Parasitic Diseases

2. Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense

3. 5'-{[(Z)-4-Amino-2-butenyl]methylamino}-5'-deoxyadenosine: a potent enzyme-activated irreversible inhibitor of S-adenosyl-L-methionine decarboxylase from Escherichia coli

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