Structural Basis for the Improved Drug Resistance Profile of New Generation Benzophenone Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors-Reference-Cited by-同舟云学术

Structural Basis for the Improved Drug Resistance Profile of New Generation Benzophenone Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

Published:2008-07-30 Issue:16 Volume:51 Page:5000-5008
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ren Jingshan¹,Chamberlain Philip P.¹,Stamp Anna¹,Short Steven A.¹,Weaver Kurt L.¹,Romines Karen R.¹,Hazen Richard¹,Freeman Andrew¹,Ferris Robert G.¹,Andrews C. Webster¹,Boone Lawrence¹,Chan Joseph H.¹,Stammers David K.¹

Affiliation:

1. Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, U.K., and GlaxoSmithKline Inc., 5 Moore Drive, Research Triangle Park, North Carolina 27709

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8004493

Reference47 articles.

1. New Developments in Anti-HIV Chemotherapy

2. Novel antiretroviral agents in HIV therapy

3. Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

4. Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance

5. Factors contributing to the inhibition of HIV reverse transcriptase by chain-terminating nucleotides in vitro and in vivo

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