Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid-Reference-Cited by-同舟云学术

Structure−Activity Relationship Study on a Simple Cationic Peptide Motif for Cellular Delivery of Antisense Peptide Nucleic Acid

Published:2005-09-15 Issue:21 Volume:48 Page:6741-6749
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Albertshofer Klaus¹,Siwkowski Andrew M.¹,Wancewicz Edward V.¹,Esau Christine C.¹,Watanabe Tanya¹,Nishihara Kenji C.¹,Kinberger Garth A.¹,Malik Leila¹,Eldrup Anne B.¹,Manoharan Muthiah¹,Geary Richard S.¹,Monia Brett P.¹,Swayze Eric E.¹,Griffey Richard H.¹,Bennett C. Frank¹,Maier Martin A.¹

Affiliation:

1. Department of Medicinal Chemistry, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050490b

Reference32 articles.

1. Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

2. PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

3. Stability of peptide nucleic acids in human serum and cellular extracts