Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis-Reference-Cited by-同舟云学术

Discovery and Early Clinical Development of 2-{6-[2-(3,5-Dichloro-4-pyridyl)acetyl]-2,3-dimethoxyphenoxy}-N-propylacetamide (LEO 29102), a Soft-Drug Inhibitor of Phosphodiesterase 4 for Topical Treatment of Atopic Dermatitis

Published:2014-07-01 Issue:14 Volume:57 Page:5893-5903
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Felding Jakob¹,Sørensen Morten D.¹,Poulsen Tina D.¹,Larsen Jens¹,Andersson Christina¹,Refer Pia¹,Engell Karen¹,Ladefoged Lotte G.¹,Thormann Thorsten¹,Vinggaard Anne Marie¹,Hegardt Pontus¹,Søhoel Anders¹,Nielsen Simon Feldbæk¹

Affiliation:

1. New Product Discovery and Global Development, LEO Pharma A/S, Industriparken 55, 2750 Ballerup, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500378a

Reference17 articles.

1. A Population-Based Survey of Eczema Prevalence in the United States

2. Quality of life and childhood atopic dermatitis: the misery of living with childhood eczema

3. Malignancy concerns of topical calcineurin inhibitors for atopic dermatitis: facts and controversies

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